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Senior Scientist

Employer
Merck KGaA
Location
Minnesota
Salary
Competitive

View more

Industry
Technology
Role
Other
Job Type
Long-Term
Hours
Full Time

Your Role:

You will work in a project-focused environment as a member of a multidisciplinary Process Development (PD) group responsible for development and qualification of manufacturing methods to support new product introduction and optimization of existing processes: Design and perform laboratory experiments and evaluate data in order to ultimately develop reliable manufacturing and/or QC methods; Regularly communicate project status to the PD, project management and Operations teams; Perform and troubleshoot initial processing of newly developed and/or scaled up procedures with the relevant Operations teams in order to qualify new methods; Aid in training and transfer of newly developed methods to the receiving Operations team to ensure long term success; Write clear instruction in operating procedures for Operations' use in ongoing future manufacturing; Apply Root Cause Analysis tools in order to address manufacturing issues; Design and develop new products focused on providing solutions for customers in the life science field; Develop manufacturing processes that may require the following: Fermentation / cell culture, extraction of proteins from plant, animal, or bacterial sources, and protein purification.

Who You Are:
Minimum Qualifications:

  • PhD in biochemistry, microbiology, molecular biology or a scientific discipline
  • 5+ years of independent lab research and/or chemical manufacturing experience
  • 3+ years of experience in protein purification and characterization, chromatography (IEX, HIC, SEC, etc.), enzymatic assay, recombinant protein expression, and microbial cell culture.
  • Preferred Qualifications:

  • Microbial genetics, molecular cloning techniques, and standard molecular biology techniques
  • Strong communication skills (both verbal and written) and ability to collaborate with Operations' departments, external customers, and worldwide internal business partners.
  • Culturing yeast or other non-E. coli microbes.
  • Automated chromatography systems (such as GE AKTA) and bioreactors / fermenters (such as Sartorius BIOSTAT)
  • Strain engineering
  • Synthetic biology
  • Mammalian cell culture
  • Immunofluorescence, Western blotting
  • RSREMD

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